Post by account_disabled on Jan 21, 2024 21:50:32 GMT -8
The Higher Council for Scientific Research (CSIC) has launched a genetic study to identify the individual risk of developing the most serious forms of Covid-19. This research, in which the Galician Supercomputing Center participates , aims to determine the genetic causes that explain why some infected people do not suffer clinical effects while others suffer very adverse reactions to the disease. The results, according to the CSIC, could help prevent serious infections and discover potential treatments .
Anna Planas, a CSIC researcher at the Barcelona Biomedical Research Institute (IIBB), who coordinates this project - named Inmugen - explains that advanced age and the presence of chronic Phone Number Database diseases increase the risk of suffering a serious reaction and of needing admission to the ICU and even dying. "However, there are also younger patients without previous pathologies who develop very severe forms of the disease for currently unknown reasons; we think that the answer could be in the genes," he says. The project proposes to study in-depth genes of innate immunity (which is the defense system with which a person is born) to explain the greater risk of each person to develop severe forms of the Covid-19 disease," explains Planas.
The Galicia Supercomputing Center will participate in the study There are small genetic variations in the normal population that can determine a different ability of people to respond to attacks caused by certain infections. That is why they will study "genetic variations focusing on innate immunity genes." "We will study the DNA of patients with severe infection and others with mild infection ," observes the researcher, who is confident that these results will help identify people at risk of becoming seriously ill, since they are the ones who will need greater protection. Researchers hope that this project will contribute to finding molecular targets for possible treatments against the disease. This project is funded by the CSIC and various multidisciplinary research teams will be involved in it.
Anna Planas, a CSIC researcher at the Barcelona Biomedical Research Institute (IIBB), who coordinates this project - named Inmugen - explains that advanced age and the presence of chronic Phone Number Database diseases increase the risk of suffering a serious reaction and of needing admission to the ICU and even dying. "However, there are also younger patients without previous pathologies who develop very severe forms of the disease for currently unknown reasons; we think that the answer could be in the genes," he says. The project proposes to study in-depth genes of innate immunity (which is the defense system with which a person is born) to explain the greater risk of each person to develop severe forms of the Covid-19 disease," explains Planas.
The Galicia Supercomputing Center will participate in the study There are small genetic variations in the normal population that can determine a different ability of people to respond to attacks caused by certain infections. That is why they will study "genetic variations focusing on innate immunity genes." "We will study the DNA of patients with severe infection and others with mild infection ," observes the researcher, who is confident that these results will help identify people at risk of becoming seriously ill, since they are the ones who will need greater protection. Researchers hope that this project will contribute to finding molecular targets for possible treatments against the disease. This project is funded by the CSIC and various multidisciplinary research teams will be involved in it.